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Anti-Human CD4 FITC
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產品型號：
 06111-50
產品報價：
產品特點：
 人外周血淋巴細胞用FITC OKT4與紅色相關的同型對照。
Human peripheral blood lymphocytes were stained with FITC OKT4 with relevant isotype control in Red.
  06111-50Anti-Human CD4 FITC的詳細資料：

The OKT4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV). CD4 is a 59 kDa single-chain transmembrane glycoprotein that expressed on the surface of most of the thymocytes, T-helper cells, and in low levels on monocytes and macrophages. CD4 is a co-receptor in the antigen-induced T cell activation (together with the MHC class II). The OKT4 and the RPA-T4 monoclonal antibodies recognize different epitopes of CD4 and they do not exhibit cross-block binding.

OKT4單克隆抗體特異性結合CD4受體為人類免疫缺陷病毒（HIV）。 CD4是一個59 kDa的單鏈跨膜糖蛋白，其表達的大多數的胸腺細胞，T輔助細胞的表面上，并在低的水平上的單核細胞和巨噬細胞。 CD4是一個共受體在抗原誘導的T細胞活化（第II類MHC在一起）。的OKT4和RPA-T4的單克隆抗體識別的CD4的不同表位和它們不表現出交叉阻斷結合。

Clone

OKT4

Format:

FITC

Applications

FC

Reactivity

Human

Isotype:

Mouse IgG2b, kappa

Research Interest:Adaptive Immunity
Cell Type:Monocytes and Macrophages, T Cells, Treg cells, Th17 cells

Preperation:

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Formulation:

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

References:

Reinherz, E. L., Kung, P. C., Goldstein, G., & Schlossman, S. F. (1979). Separation of functional subsets of human T cells by a monoclonal antibody.Proceedings of the National Academy of Sciences, 76(8), 4061-4065.

 Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Bour, S. T. E. P. H. A. N. E., Boulerice, F. R. A. N. C. O. I. S., & Wainberg, M. A. (1991). Inhibition of gp160 and CD4 maturation in U937 cells after both defective and productive infections by human immunodeficiency virus type 1.Journal of virology, 65(12), 6387-6396.
產品相關關鍵字： Anti-Human CD4 FITC 06111-50 CD4單抗 CD4 單克隆抗體
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